ABSTRACT
To compare the effects of nalbuphine and midazolam on cardiovascular response to laryngoscopy and intubation -during induction of anaesthesia. Ninety adult male patients of ASA I or II status were included and divided into three equal g roups. Group I was control in which 3ml of saline was given. Group II received nalbuphine 75 ug/kg and Group III received midazolam 30 ug/kg. The cardiovascular response was evaluated at laryngoscopy and every minute after intubation for three minutes.The results were analysed statistically by ANOVA.p<0.05 was taken significant. A decrease in HR, SBP, DBP, MAP was seen after three minutes in Group II and III but the decrease was more pronounced in Group II.[p<0.05] Premedication with nalbuphine 75gg/kg is more effective than midazolam in blunting the haemodynamic response to laryngoscopy and intubation
Subject(s)
Humans , Male , Laryngoscopy/adverse effects , Intubation, Intratracheal/adverse effects , Nalbuphine , Midazolam , Anesthesia , Heart Rate/drug effects , Blood Pressure/drug effects , Intraocular Pressure/drug effects , Catecholamines , Arrhythmias, Cardiac/etiology , Myocardial Infarction/etiology , Ventricular Dysfunction, Left/etiology , Cerebral Hemorrhage/etiologyABSTRACT
To evaluate the occurrence of postoperative sore throat after the use of LMA among patients undergoing surgery on intermittent positive pressure ventilation and those on spontaneous mode. hundred adult patients of ASA I or II status were included and divided into two equal groups. Group I patients were randomly assigned for positive pressure ventilation and group II patients for spontaneous breathing. Anaesthesia was administered with propofol, oxygen nitrous oxide and halothane. The LMA of appropriate size was placed.After completion of surgery, LMA was removed when the patient regained deglutition reflex. Patient was questioned postoperatively for variables of sore throat for three days. In group I, 12% patients complained of mild sore throat in comparison to group II where 6% suffered from mild sore throat [p>0.05]. There was no difference in the discomfort levels among males and females. Pharyngolaryngeal discomfort is less after use of LMA under spontaneous ve ntilation in comparison to controlled ventilation